IEEE SENSORS 2009 Conference - 25-28 October 2009

Tutorials

Micro-Optic and
Fiber Optic Sensors

Terahertz Sensing

Noise Harvesting

Chemical and Gas
Sensing

Industrial Tomography

Silicon Piezoresistive
Stress Sensors

Miniaturised
Space Payloads

Integrated Gas Sensors

Sensors as
Communication Channels

Nanophotonic Sensors

Biopolymer Detection

Integrated
Radar Sensors

Ultrasonics

Title:	Sensors for Biopolymer Detection by Electrochemical and Optical Methods
Speaker:	Vladimir Vetterl - Acadmey of Sciences, Czech Republic

Abstract
Description of tutorial scope:
1. Polymers (molecular weight, spatial structure, properties)
     1.1. Dental polymers
     1.2. Biopolymers
          1.2.1. Nucleic acids
          1.2.2. Human blood plasma proteins.
          1.2.3. Polysacharides
2. Electric and Magnetic Properties of Nucleic Acids
     2.1. Electric properties
          2.1.1. Electronic charge distribution
          2.1.2. Interactions of bases, nucleosides and nucleoti¬des with ions
          2.1.3. Forces stabilizing double helical conformation of DNA and synthetic polynucleotides
          2.1.4. Electric field effects on DNA
     2.2. Magnetic properties
          2.2.1. Diamagnetic anisotropy
          2.2.2. Degree of orientation of nucleic acids in magne¬tic field
3.Sensing of biopolymers interaction with surfaces by electrochemical methods.
     3.1. Electrocapillary curves, potential of electrocapillary maximum.
     3.2. Electrode double layer.
     3.3. Electrochemical methods and instrumentations.
          3.3.1. Polarography.
          3.3.2. Impedance measurements, electrochemical impedance spectroscopy.
          3.3.3. Measurement of electrocapillary curves.
     3.4. Adsorption
          3.4.1. Effect of adsorption on electrocapillary curves
          3.4.2. Adsorption isotherms.
     3.5. Two-dimensional condensation, Avrami equation.
     3.6. Electrochemical properties of nucleic acids.
          3.6.1. Faradayic properties, reduction, oxydation.
          3.6.2. Tensammetric properties.
4. Sensing of biopolymers interaction with surfaces by optical methods - difraction optical element (DOE).
5. Titanium implants:
     5.1. Interaction of metal with tissues
     5.2. Adsorption of human blood plasma proteins on the titanium surrface.

Biography

EDUCATION:
1953 - 1958	Faculty of Science, Department of Physics, Masaryk University, Brno, diploma thesis: The design of the Stark radiospectroscope (Master degree)
1958 - 1962	Faculty of Medicine, Masaryk University, Brno
1960 - 1963	Postgraduate training, Institute of Biophysics, 1964 PhD (CSc.) thesis: Electric properties of DNA
1992	Dissertation: Intermolecular interactions of nucleic acid components, promoted to associate professor
1996	promoted to a professorship in biophysics
1999	promoted to doctor of science (DrSc.)
EXPERIENCE:
1968 - 1969	Postdoctoral fellow, Centre d'etudes nucleaires, Saclay, France
1989 - 1990	Senior research associate, Department of Chemistry, Georgetown University, Washington D.C., USA
AWARDS:
1994	Gold J. Heyrovsky honorary medal for merit in the chemical sciences, award of the Academy Council of the Academy of Sciences of the Czech Republic
1999	Silver Medal of Palacky University for merit in education of medical biophysics

RESEARCH INTERESTS: Physical chemistry of nucleic acids, electrochemistry, spectra UV, CD, NMR, intermolecular interactions.

PUBLICATIONS: More than 60 scientific publications, 4 review papers in monographies. According to WOS: h-index 17, number of citations 1083.